Essay On Cystic Fibrosis Words | 5 Pages. Abstract Cystic fibrosis is a life-threatening, genetic disease that causes persistent lung infections, and complicates a person’s ability to breathe. People with Cystic fibrosis have troubles to breathe because a broken gene causes a thick, growth of mucus in the lungs, pancreas and other organs Cystic Fibrosis Essay Words | 5 Pages. Cystic Fibrosis is a severe hereditary disease that infects the lungs, digestive system, sweat glands and male fertility. The name Cystic Fibrosis derives from the Fibrous scar tissue that develops in the pancreas Essays About Cystic Fibrosis. Essay examples. Essay topics. Cystic Fibrosis: a Genetic Disease. word | 1 Page. Cystic Fibrosis is a genetic disease that creates issues in many of the organs. It has various effects and the level of severity varies for everyone affected. Cystic Fibrosis is a defective gene that causes the body to produce
What Is Cystic Fibrosis Essay Example For Students - words | Artscolumbia
Cystic Fibroids Cystic fibrosis Cystic fibrosis is a disease that can be passed down from one generation to the other. It affects secretary glands that produce mucus and sweat. Cystic fibrosis essay disease results after the fibrosis transmembrane conductance regulator CFTR gene that is found on chromosome 7 has undergone some sort of mutation. Mutation on chromosome 7 alters the production and function of CFTR glycoprotein Scott, Studies have identified more than variations of CFTR mutations. Significant numbers of cystic fibrosis patients have amino acid defects.
The amino acid mutation basically occurs when Cystic fibrosis essay protein is missing 3 base pairs at position on CFTR protein sequence which codes for phenylalanine. Phenylalanine is essential in nutrition. There are other mutations that mainly occur in non-white populations Scott, The CFTR mutations interfere with how sodium and chloride is transported on the apical surface level of exocrine gland epithelial cells. Cystic fibrosis presents in the epithelial cells of patient's respiratory avenues, sweat glands, gastrointestinal tracts, and genitourinary systems. This causes dehydration and production of thick secretions in a number of organs.
Lungs, sinuses, pancreas, intestines, hepatobiliary tree, and vas deferens are mostly affected. Worse still a bigger portion of the population are still asymptomatic carriers. This is some news that the healthcare service providers and the larger community should be worried about, cystic fibrosis essay. Bearing in mind that this is a genetic disorder and that the number of asymptomatic carriers have not been accounted for it can as well be that over half of the United States population carries this defective gene that causes cystic fibrosis Scott, The fact that the disease presents in epithelial cells of patient's airways should be a worry to the healthcare practitioners.
Thick secretions that are resultantly produced in the lungs are likely to interfere with patient's respiratory system which can be fatal if not mitigated in good cystic fibrosis essay. This should not be any form of news to us because we all clearly know that the lungs facilitate uptake of oxygen that is pivotal in energy transduction process and the removal of gases that are produced in the process of energy production that cannot be used by the human system Scott, Diagnosis Cystic fibrosis can be diagnosed using biochemical or genetic testing avenues. Phenotypic features like gastrointestinal and nutritional abnormalities, cystic fibrosis essay, salt-loss syndrome, and male urogenital abnormalities could be an indication that a person is suffering cystic fibrosis Scott, When a new borne baby suffers from intestinal obstruction where stool gets stuck in the bowel, this could be one of the earliest manifestations of the disease.
Twenty percent of infants with cystic fibrosis develop this kind of obstruction. This could be some early indication that somebody is suffering from cystic fibrosis. They may also exhibit electrolyte imbalance, nasal polyps and cystic fibrosis essay disease, rectal prolapse, and reproductive complications, cystic fibrosis essay. Adults with cystic fibrosis tend to live longer and therefore develop non-respiratory symptoms. Children with cystic fibrosis are cystic fibrosis essay by the age of one year.
Coughing is predominant in early stages of this disease. Children with ages below ten cystic fibrosis essay experience chronic coughing, cystic fibrosis essay. A number of tests can be performed when cystic fibrosis is suspected. Such tests include prenatal genetic testing, ultrasonography, and amniocentesis. The most frequently used test is a sweat chloride test. The test is facilitated by stimulating the sweat glands of the patient's forearm or thigh with pilocarpine. Sweat is subsequently collected and analyzed to determine the chloride level. One percent of patients with unusual genotypes of cystic fibrosis have normal sweat chloride concentrations.
After a genetic test has been conducted and the result shows 2 CFTR mutations a second sweat test has to be conducted to confirm presence of cystic fibrosis in these patients. Other diagnostic tests should be employed cystic fibrosis essay case sweat chloride tests are inconclusive. Nasal potential difference should therefore be performed Scott, Other tests to be done incase of inconclusive sweat chloride tests should be the CT of the chest and the sinuses, bronchoscopy with bronchial lavage to culture bacteriain the lower airway, pancreatic imaging, and ultrasonography Some modern neonatal screening tests can be done to help in proactive treatment of cystic fibrosis Scott, This kind of test helps in preventing symptoms before they appear.
This test helps in evaluation of immunoreactive trypsinogen levels. It also involves analysis of deoxyribonucleic acid for CFTR mutations. Early detection of cystic fibrosis in children has massive health benefit to these children especially under circumstances when neonatal screening is used to diagnose cystic fibrosis essay disease. Patients with cystic fibrosis are subjected to medical imaging examination as it helps in monitoring the disease pathologic changes. Because female organs are more radio -- sensitive women patients with cystic fibrosis have increased incidence risk ratio for all cancers. Patients with cystic fibrosis mainly succumb to respiratory fatalities.
These patients should therefore be subjected to frequent diagnostic imaging of cystic fibrosis essay gastrointestinal system to amicably address this disease's GI manifestations. Children should not be exposed to too much radiation. Radiation exposure can also be reduced by minimizing unnecessary supra-apical and infrapulmonary imaging on CT scans. Thyroid and breast cancer shields are also effective when pediatric patients are subjected to radiographic and CT studies. Some of the respiratory manifestations of cystic fibrosis are presence of thickened secretions that come about when there is too much chloride and too much sodium transport from the mucous.
Sticky mucus obstructs airflow in bronchioles and small bronchi Gould, With time patients develop bronchiectasis. This results into loss of elasticity, muscle integrity, and cartilage, cystic fibrosis essay. Impaired mucociliary clearance causes stagnant mucous to harbor bacterial growth and infection, cystic fibrosis essay. Mucous plugs the airways and encourages persistence of bacteria and airway damage. Production of highly viscous secretions blocks the airways and promotes vasoconstriction of micro vessels leading to altered ventilation-perfusion Gould, cystic fibrosis essay, Chest radiography is one of the preferred methods used in initial evaluation of respiratory disease related to cystic fibrosis because it requires low radiation dose.
Other method used is sinus imaging that is used to ascertain degree of sinus impairment. It helps in evaluation of bronchochiectasis and tracheobronchial anatomy. Magnetic resonance imaging is also used in evaluation of patients with cystic fibrosis. It is appropriate for vascular and mediastinal anatomy evaluation. Treatment Treatment regimes are directed at preventing upper respiratory infections which are responsible for highest number of deaths in people with cystic fibrosis. Medications include mucolytic agents and bronchodilators which are used to thin out the thick tenacious mucous. Use of broad spectrum prophylactic antibiotics is also recommended Scott, Postural drainage, percussion, coughing techniques, and breathing exercises also help patients dislodge secretions.
Antibiotics treat the primary stimulus. Patients with mild lung disease can use corticosteroids especially those that are inhaled Scott, High dose ibuprofen can be used to inhibit lung deterioration. Bronchial artery embolization helps in treating significant hemoptysis. Other treatment regimes involve direct delivery of glycerin and amphotericin Cystic fibrosis essay. via intracavitary percutaneous instillation with CT guidance and lung transplantation Scott, Methods To access information about this disease I typed Google scholar into Google search engine. Into the Google Scholar home page I typed cystic fibroids, cystic fibrosis essay. A host or researches that had been done on cystic fibroids appeared ranging from systematic reviews to peer reviewed scientific journal articles appeared.
I chose recent journal publications and systematic reviews, cystic fibrosis essay. Publications from reputable scientific research bodies majoring on human health research like the Center for Disease Control were also considered, cystic fibrosis essay. Cystic fibrosis essay did use some academic databases like NCBI. However, the only problem I encountered with them was that subscription was a requisite. There was no problem when it came to narrowing down on one particular search because I knew cystic fibrosis was one major respiratory challenge to many.
Case study A patient was brought to the hospital I was undergoing clinical practice who was suffering from intestinal obstruction. This patient exhibited some other symptoms. He had sticky mucous that accumulated and obstructed airflow in bronchioles and small bronchi. The chronic inflammation caused…. References List Gould, B. Pathophysiology for the Health Professions. Philadelphia, PA: Saunders. Jones, A. Emerging treatments in cystic fibrosis. Cystic Fibrosis CF is genetically inherited through a defective gene, which results in the body producing "abnormally thick and sticky fluid, called mucus. This mucus builds up in the breathing passages of the lungs and in the pancreas, the organ that helps to break down and absorb food.
Cystic Fibrosis: The Facts is a comprehensive, informative, and well-written book about the disease and its treatments. Ann Harris and Maurice Super address the book to a cystic fibrosis essay audience, making the book extremely accessible to laypeople. Cystic Fibrosis: The Facts is an ideal source for people suffering from cystic fibrosis or for people who have loved ones suffering from the disease. Harris and Super divide the page book into several. As the text by Davis indicates, cystic fibrosis essay, "as mutational analysis and patient data continue to be compiled, patient genotyping should prove useful in both prognosticating and providing a framework for evaluating. There is a wealth of available information, data and studies on CF. What it all means to the patients who suffer from this debilitating and life-threatening disease will be understood as this essay proceeds.
CYSTIC FIBROSIS, Causes, Signs and Symptoms, Diagnosis and Treatment.
, time: 6:26Cystic Fibrosis Essay | Rebecca Grainger - blogger.com
What Is Cystic Fibrosis Essay. Cystic fibrosis is the most common autosomal recessive genetic disease of white Indo-Europeans (Caucasians). Three main systems are usually affected by cystic fibrosis. These include the lungs and respiratory tract, the digestive tract (especially the pancreas and intestines) and the sweat glands Cystic Fibrosis. Cirrhosis of the Liver Essay. words 3 pages. Introduction The liver can regenerate damaged cells due to its hearty nature. However, a long exposure of chronic viral infections or alcohol can lead to irreversible damages. The irreversible scarring of the liver due to loss of the liver cells causes liver cirrhosis Jun 17, · Cystic Fibrosis (CF) was earlier referred to as ‘mucoviscidosis’. It is a disease marked by an ineffective chloride channel. It was first diagnosed in the s by tasting salty sweat when parents kissed their child on the forehead (Littlewood, ). The increased chloride (Cl-) ion concentration of sweat is still the main diagnosis of CF
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